Novartis drug candidate scores interim win in rare kidney disease trial https://ift.tt/cmBey4a

Treatment with the drug candidate, acquired as part of the purchase of US biotech firm Chinook for up to $3.5 billion, resulted in a meaningful improvement in proteinuria in patients suffering from IgA nephropathy when compared to placebo, the Swiss drugmaker said in a statement.

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Bluebird bio to sell sickle cell FDA voucher for $103 mln if therapy approved https://ift.tt/iZTh91m

The voucher, which is transferable, allows a drug developer to expedite the review process of its product even if it does not fit requirements for a quick process. This would be the third priority voucher sale for bluebird after selling two for a combined $197 million over the past one year.

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COVID vaccination didn't increase risk of sudden deaths among young adults in India: Study https://ift.tt/iZTh91m

The study was conducted to investigate the factors contributing to sudden unexplained deaths among healthy young adults in India. The study included cases of apparently healthy individuals aged 18-45 years with no underlying health issues who died suddenly from unexplained causes between October 1, 2021 and March 31, 2023.

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Top 20 global biopharmaceutical firms experience varied market capitalisation shifts in Q3 2023: GlobalData https://ift.tt/iZTh91m

Out of the top 20 companies, nine saw their market capitalisation surge by more than 10 per cent, with significant gains achieved by Amgen (22.1 per cent), Lilly (16.1 per cent), Regeneron Pharmaceuticals (14.9 per cent), Novo Nordisk (13.9 per cent), and AbbVie (13.1 per cent).

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"In India, we follow holistic, inclusive approach", says Union Health Minister Mansukh Mandaviya https://ift.tt/8modnwD

Speaking at the 76th session of the WHO Regional Committee for SEARO, Union Health Minister Mansukh Mandaviya stated that India's approach has been holistic to ensure affordable healthcare to its citizens, adding that India is committed to "leaving no one behind".

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US shifting COVID antivirals to commercial market on Nov. 1 https://ift.tt/8modnwD

The government has been overseeing distribution of the treatments, alongside vaccines and tests, but has transferring that work to traditional commercial channels. Commercial ordering for the treatments is set to start on Nov. 1. The U.S. government paid around $530 per course for Paxlovid, the most commonly prescribed at home COVID-19 treatment in the country, and made it available at no cost.

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Study shows that gut fungus has a long-term impact on the immunological response to severe COVID-19 https://ift.tt/HGcemDC

This research indicates a subset of individuals who could benefit from specialised, yet-to-be-determined treatments. Using patient samples and preclinical models, the researchers discovered that the proliferation of fungus in the intestine, particularly Candida albicans yeast strains, causes an increase in immune cells whose actions can exacerbate lung injury.

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Health Ministers to nominate next WHO Regional Director for South-East Asia https://ift.tt/HGcemDC

The 76th Session of the WHO Regional Committee for South-East Asia, the annual governing body meeting of the world body at the regional level, will be held from October 30 to November 3, in the national capital. WHO Director-General Tedros Adhanom Ghebreyesus and WHO South-East Asia Regional Director Poonam Khetrapal will be present.

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US FDA advisers to determine need for more studies of Vertex/CRISPR gene therapy https://ift.tt/HGcemDC

The therapy, called exagamglogene autotemcel or exa-cel, uses new gene editing CRISPR technology, and is the first-of-its-kind product to reach the FDA for an approval decision.

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Strides Pharma sells its Singapore manufacturing site for $15 million https://ift.tt/CA2IGQd

This sale will also help Strides to reduce annual costs by Rs 75 crore, of which Rs 18 crore will be reduction in operating expenses and Rs 57 crore in depreciation and operating lease expenses. Strides said the Transaction would be EPS (earnings per share) accretive with no impact on revenues.

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Norms violated in hiring of pharma university faculty: Probe https://ift.tt/CA2IGQd

Lieutenant governor VK Saxena has forwarded the report to the chief secretary to instruct the directorate of training and technical education to examine the report within 30 days and recommend specific action as per law against those found involved in violating the recruitment rules. The vigilance inquiry observed that eligibility criteria had been violated in the recruitment process.

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Delhi govt to hike number of medical education seats to 1,070 in three years https://ift.tt/CA2IGQd

The National Medical Commission (NMC) recently asked medical colleges to submit applications for increasing seats for postgraduate (PG) medical courses for the 2024-25 academic year.

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Weight-loss drugs in spotlight as pharma services firms rush to snap up business https://ift.tt/CA2IGQd

A surge in sales of Novo Nordisk's drug Wegovy, which launched in the United States in mid-2021, has propelled the Danish drugmaker to become Europe's most valuable company.Amid a global obesity crisis, some analysts predict the market for weight-loss drugs could be worth $100 billion by 2030. Some companies, like West Pharmaceutical Services, whose share price is up 37 per cent year to date, are already providing components for the injections pens and reaping rich rewards from the business.

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FDA warns about giving probiotics to preterm babies after infant death, other injuries https://ift.tt/CA2IGQd

The agency issued warning letters to two companies accused of illegally marketing the probiotics products, including Abbott Laboratories, which was at the center of a recall and nationwide shortage of powdered infant formula last year.

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Brazil scientists developing new 'vaccine' for cocaine addiction https://ift.tt/9jUF53E

Dubbed "Calixcoca," the test vaccine, which has shown promising results in trials on animals, triggers an immune response that blocks cocaine and crack from reaching the brain, which researchers hope will help users break the cycle of addiction.

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Monoclonal antibodies for Nipah treatment to be developed indigenously: Kerala Health Minister https://ift.tt/9jUF53E

The Kerala government's Institute of Advanced Virology, the Rajiv Gandhi Centre for Biotechnology (RGCB) and the National Institute of Virology in Pune would be involved in the effort.

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US FDA approves new therapy for myelodysplastic syndromes a rare form of blood cancers https://ift.tt/9jUF53E

The US FDA granted the approval of Tibsovo to Servier Pharmaceuticals LLC and RealTime IDH1 Assay to Abbott Laboratories. MDS are a rare form of blood cancers that can occur when the mutations in the bone marrow progenitor cells (cells that form blood) lead to insufficient numbers of healthy blood cells.

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Blackstone-owned Health Platform Quality Care to buy KIMS Kerala https://ift.tt/9jUF53E

Quality Care India Limited (QCIL), a hospital platform owned by Blackstone, has agreed to acquire KIMS Health Management (KHML), Kerala's leading hospital chain, for ₹3,500 crore ($400 million). With this acquisition, QCIL will become the fourth largest hospital group in India, owning close to 3,800 beds.

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AI is a cure and curse for PGI: Fine for patient care, but not for thesis https://ift.tt/McdjWeY

The Post Graduate Institute of Medical Education and Research (PGI) in Chandigarh has issued an order stating that a thesis written using generative AI tools will not be accepted. While the hospital is using AI for patient care and queue management, the administration believes that AI assistance in thesis writing compromises originality and academic standards.

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WHO's move for regulation of AI in healthcare highlights risks: Report https://ift.tt/McdjWeY

The report by GlobalData, a data and analytics company, notes that AI technologies are and have been deployed quite quickly, and not always with a full understanding of how they will work in the long run, which could be harmful to healthcare professionals or patients.

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Higher blood transfusion during heart surgery may increase patient mortality risk https://ift.tt/McdjWeY

When blood transfusions are administered, or in cases where there are pulmonary complications in the lungs, patients may experience complications such as pneumonia and lung infections. Additionally, renal dysfunction is another concern, which manifests as elevated creatinine levels and reduced urine output when a significant volume of blood is transfused.

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Gambia trial opens over cough children's syrup deaths https://ift.tt/McdjWeY

A trial opened Tuesday in The Gambia's capital Banjul over the deaths of small children who took a cough syrup made by the India-based Maiden Pharmaceuticals. Beginning in September last year, The Gambia ordered a recall of several cough and cold medications, as well as all products manufactured by the Indian laboratory Maiden Pharmaceuticals from which the adulterated syrups originated, after the deaths from kidney failure of at least 70 young children.

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No case of negligence if complications unrelated to medical procedure: SC https://ift.tt/nxbQo4z

The court noted that no case of negligence is made out if complications suffered by the patients are not related to the medical process.

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Merck discontinues some cancer drug development with China's Sichuan Kelun https://ift.tt/nxbQo4z

The move comes days after Merck said it would pay Daiichi Sankyo $5.5 billion to jointly develop three of its candidate cancer drugs in a deal that could be worth up to $22 billion for the Japanese firm. Merck is aiming for at least $6 billion in revenue from its oncology business in the fiscal year ending March 31, 2026, which would represent about a five-fold increase over a three-year period.

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Pfizer’s Penbraya vaccine receives USFDA approval for most common serogroups causing meningococcal disease in adolescents https://ift.tt/nxbQo4z

Penbraya(meningococcal groups A, B, C, W, and Y vaccine), the first and only pentavalent vaccine reduces the total number of doses needed for individuals to be fully vaccinated against the five most common serogroups, thereby streamlining the standard of care and potentially increasing the number of adolescents and young adults vaccinated, a statement said.

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Old protocol to remain despite ICMR study on dengue lineage https://ift.tt/oAUes9J

ICMR funded a report that called for ‘surveillance and risk assessment in this strategically important part of the country to decipher its outbreak and severe disease-causing potential’. Study also highlighted the urgent need of surveillance and clinical characterisation of dengue fever.

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Fake antibiotic medicines worth Rs 17.5 lakh seized in raids across Gujarat; 4 held https://ift.tt/oAUes9J

Acting on a tip-off, the Ahmedabad office of the food and drug regulator nabbed one Khimaram Kumhar in Ahmedabad with 99 boxes of POSMOX CV 625 antibiotic tablets worth Rs 2,61,250 on Friday.

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India sends medical aid, disaster relief material for people of Palestine https://ift.tt/oAUes9J

The medical supplies include essential life-saving medicines and protective and surgical items aimed at handling emergency medical conditions. While arranging the medical supply, wound care was also taken into consideration

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Submit admission details or face action: NMC to medical colleges https://ift.tt/oAUes9J

Sources said medical colleges have to submit details of new students to the NMC after the admission process is over. Once the admission deadline passed, the commission reminded colleges to submit the details by October 20.

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Delhi's air quality continues to remain in 'poor' category with AQI of 266 https://ift.tt/oAUes9J

According to the System of Air Quality and Weather Forecasting and Research (SAFAR), the air quality in Kartavya Path at India Gate was recorded at 266, IGI Terminal T3 in New Delhi at 276. Meanwhile, Noida recorded an AQI of 290 (poor) and Gurugram 152 (moderate). Anand Vihar breached the very poor category in New Delhi with an AQI of 345, IT0 with an AQI of 309, New Moti Bagh with an AQI of 360, Dwarkar Sector-8 recorded an AQI of 313.

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EU clears Pfizer's $43 bn takeover of biotech firm Seagen https://ift.tt/dU3yrZD

Pfizer announced in March its deal with Seagen, which is based in Washington state and leads in the research, development and commercialisation of cancer treatments.

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Daiichi Sankyo, Merck ink $22-billion cancer drug deal https://ift.tt/dU3yrZD

Daiichi rose as much as 18 per cent on Friday, the biggest intraday jump since 2005, after Merck agreed to pay $4 billion upfront and as much as $22 billion to develop and market three cancer drug candidates. One them is them slated to seek US approval by March 2024, the company said in a statement. Daiichi will retain the rights for these drugs in Japan.

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Pig heart transplant recipient reaches 1-month mark, pushing through physical therapy https://ift.tt/zOlxBJU

The Maryland team last year performed the world's first transplant of a heart from a genetically altered pig into another dying man. David Bennett survived just two months before that heart failed, for reasons that aren't completely clear although signs of a pig virus later were found inside the organ. Lessons from that first experiment led to changes before this second try, including better virus testing.

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600 MBBS students to lose seats in NMC crackdown https://ift.tt/zOlxBJU

While admissions to more than 1,500 MBBS seats were time-barred and remained vacant even after the September 30 deadline set by the Supreme Court, admissions of another 600 students are in jeopardy as their admissions were invalidated by the National Medical Commission (NMC). These students were admitted by colleges in violation of rules that only a central or state agency can conduct counselling.

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141 MBBS admissions cancelled as centralised process order ignored https://ift.tt/zOlxBJU

In an order issued by the commission on Thursday, it condemned the state government move to allow admissions at institute level and said that the notice issued by the state CET cell on September 26 for filling vacant seats was issued in clear violation of the NMC directive. Till last year, admissions in the last round were conducted at the institute level. This year, in order to make the process transparent, the NMC had asked authorities to fill 100 per cent seats in all private colleges centrally in the online mode in respective states.

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141 MBBS admissions cancelled as centralised process order ignored https://ift.tt/zOlxBJU

In an order issued by the commission on Thursday, it condemned the state government move to allow admissions at institute level and said that the notice issued by the state CET cell on September 26 for filling vacant seats was issued in clear violation of the NMC directive. Till last year, admissions in the last round were conducted at the institute level. This year, in order to make the process transparent, the NMC had asked authorities to fill 100 per cent seats in all private colleges centrally in the online mode in respective states.

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WHO, dist health depts differ on filariasis drive coverage https://ift.tt/zOlxBJU

The World Health Organisation (WHO) has raised concerns over a specific lymphatic filariasis (LF) elimination push in Thane and Nagpur, two districts of Maharashtra, after noting lower coverage rates than the field teams had first claimed.

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Biocon shares decline over 6 pc; mcap plunges Rs 1,896.95 crore https://ift.tt/i3QqtRI

As per the USFDA, OAI implies that the regulator may withhold approval of any pending product applications or supplements filed from such facility till the outstanding observations related to non-compliance of manufacturing norms laid down by it.

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Pfizer to price COVID treatment Paxlovid at $1,390 per course https://ift.tt/i3QqtRI

The new list price, which does not include rebates and other discounts to insurers and pharmacy benefit managers, is $1,390 per course, Pfizer said in an emailed statement. The U.S. government paid around $530 per course for Paxlovid it has made available to Americans at no cost.

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State opens registration for BDS amid uncertainty over vacant MBBS seats https://ift.tt/i3QqtRI

Tamil Nadu has completed at least four rounds of counselling and is left with 206 BDS seats including two seats in the government quota. Based on the directorate-general of health services notification on October 13, the state selection committee announced that fresh registration for BDS will begin on Wednesday. The last date for registration will end at 5 pm on Thursday.

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Abbott profit beats on strong sales of medical devices, diagnostics https://ift.tt/i3QqtRI

The company is seeing a recovery in sales of its medical devices such as heart valves and pacemakers as more people, especially older patients, opt for surgeries that were put off during the pandemic.

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Indian medicine, homeopathy admissions begin https://ift.tt/puyXxG2

There are 4,411 eligible applications for 2,063 seats in undergraduate Indian medicine and homeopathy courses in 33 colleges – including five government colleges, he said. The selection committee has received 2,530 applications for government and government quota seats. Out of these, 556 candidates are eligible to apply under the 7.5 per cent government school student quota. The state has received 968 applications under the management quota and 913 applications under all-India quota.

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Thermo Fisher Scientific to buy Olink in $3.1 billion deal https://ift.tt/puyXxG2

The deal lifted Olink's U.S.-listed shares nearly 67 per cent in early trading, while shares of Thermo Fisher were down over 1 per cent. Thermo Fisher has been struggling with softening demand for its life sciences offerings, which includes discovery and production of new drugs and vaccines, as its biotech clients face a funding crunch.

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Menopause can be a risk factor for cardiovascular disease, finds study https://ift.tt/puyXxG2

The paper emphasises the need to see and address these risk factors to empower women and healthcare providers in preventing the development of CVD — a range of conditions affecting the heart and blood vessels, including coronary heart disease, stroke, and vascular dementia.

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SC refuses to grant legal validation to same-sex marriage but bats for protection of queer rights https://ift.tt/puyXxG2

The Supreme Court refused to acknowledge same-sex marriage on Tuesday, dealing a blow to advocates for gay rights, stating that there was "no unqualified right" to marriage except from those that are established by law. All the five judges were unanimous in refusing to accord legal recognition to same-sex marriage under the Special Marriage Act and observed it is within Parliament's ambit to change the law for validating such union.

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Italy to charge foreigners 2,000 euros a year for health service https://ift.tt/TRSNZPh

The charge, part of the 2024 budget adopted by the cabinet, will apply only to citizens from outside the European Union, the economy ministry said in a statement. The ministry said there would be an unspecified discount for those with legal residency papers, as well as for foreign students and au pairs.

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India can address neonatal mortality burden via technology and infrastructure https://ift.tt/TRSNZPh

India bears a substantial burden of preterm births, accounting for approximately one-third of all neonatal deaths in the country. EThealthworld engaged with some health experts on how the disparity in neonatal intensive care unit (NICU) availability in tier II-III cities and remote areas can be addressed and some of the challenges that must be overcome to realise India's Child Health Mission goal of reducing neonatal deaths to less than 10 per 1000 live babies by 2030.

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Drug used in diabetes treatment Mounjaro helped dieters shed 60 pounds, study finds https://ift.tt/TRSNZPh

The new study, which was funded by Eli Lilly, enrolled about 800 people who had obesity or were overweight with a weight-related health complication - but not diabetes. On average, study participants weighed about 241 pounds (109.5 kilograms) to start and had a body-mass index - a common measure of obesity - of about 38.

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Supreme court verdict today on right to marry for LGBTQIA+ people https://ift.tt/TRSNZPh

The Supreme Court of India is set to deliver its verdict on a batch of petitions by the LGBTQIA+ community seeking the right to marriage under the Special Marriage Act. The community argues that discrimination based on sexual orientation and gender identity violates constitutional guarantees of equality, non-discrimination, freedom of expression, privacy, and dignity.

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Heart failure market to be valued at $53 bn by 2032 across 7MM: GlobalData forecast https://ift.tt/TRSNZPh

The pressure for pharmaceutical companies to be more innovative with their therapies and tackle unmet needs is increasing. Companies are approaching the HF market with the strategies of optimising treatment safety and compliance, as well as developing novel drug classes: Kajal Jaddoo

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BioNTech warns of write-off of up to 900 mln euros on COVID vaccine https://ift.tt/TRSNZPh

Hit by a plunge in use of pandemic-related products, Pfizer on Friday said it would take $900 million in write-offs and other charges for their jointly developed Comirnaty vaccine, on top of much larger write-offs on Pfizer's own COVID treatment Paxlovid.

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Gaza's crowded hospitals near breaking point as Israeli ground invasion looms https://ift.tt/TRSNZPh

Much of Hamas' military infrastructure is concealed in urban areas, where street-by-street fighting would likely cause mounting casualties on both sides. Israel has given no timetable for a ground incursion.

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Study shows gut microbiome may predict colorectal cancer risk https://ift.tt/UMBxtIG

Gut bacteria may be linked with the onset of colorectal lesions and cancers, finds a study. The findings, presented at the United European Gastroenterology (UEG) Week 2023 held in Denmark, opens promising new avenues for enhancing the detection and prevention of colorectal cancer.

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About 52 per cent cases of cervical cancer diagnosed from 2012-15 survived: Lancet Study https://ift.tt/UMBxtIG

The overall survival rate of 52 per cent was about 6 per cent higher than that recorded in the previous SurvCan survey-3, which was 46 per cent. The survey presented a 5-year cancer survival assessment for selected PBCRs in India from 1991 to 1999.

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WHO plane carrying medical supplies for people of Gaza lands in Egypt https://ift.tt/UMBxtIG

WHO Director-General Tedros Adhanom Ghebreyesus reiterated his call on Israel to reconsider its decision to evacuate 1.1 million people in Gaza. His remarks come after Israeli Defence Forces urged residents of Gaza to move from the northern part to the southern part of the enclave.

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95 per cent of healthcare associated infections are device-related: Study https://ift.tt/EQf42ZX

The study highlighted a high rate of antimicrobial resistance in these infections, said Dr Purva Mathur, Professor, Microbiology Unit at AIIMS Trauma Centre. This surveillance network has been established and led by Jai Prakash Narayan Apex Trauma Center at AIIMS with the technical support of ICMR at AIIMS, New Delhi and partnership from National Centre for Disease Control (NCDC).

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Centre committed to improving health infrastructure in northeast: Health minister https://ift.tt/EQf42ZX

Mandaviya inaugurated a new regional cancer centre, an under-graduate medical college, a new building for the nursing college, hostels, eight modular operation theatres, a virtual autopsy facility and a new guesthouse at the North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS) in Shillong, Meghalaya on Saturday.

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90 per cent cheaper cancer treatment gets nod, to be offered in 20 hospitals https://ift.tt/EQf42ZX

Under the therapy, blood is taken from the patient and the T-cells, which help the immune system fight back diseases, are genetically modified or re-engineered by adding lentiviral vectors. These genetically modified cells are then injected back into the patient where they attack and kill cancer cells.

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WHO pleads for immediate reversal of Gaza evacuation order to protect health, reduce suffering https://ift.tt/EQf42ZX

The Palestinian Ministry of Health has informed the WHO that it is impossible to evacuate vulnerable hospital patients without endangering their lives. Vulnerable patients include those who are critically injured or dependent on life support. Moving them amid hostilities puts their lives at immediate risk.

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Abortion plea: SC for 2nd opinion on condition of foetus, mother https://ift.tt/pwR9cZ3

Caught in the interplay of law, ethics and morality in the case of a 26-week-old healthy and viable foetus's right to natural gestational life and the carrying woman's choice to terminate her pregnancy, the SC on Friday decided to seek a fresh report from a medical board in AIIMS on the unborn child's condition and the woman's mental state.

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Termination of pregnancy: SC seeks report from AIIMS medical board on condition of foetus https://ift.tt/pwR9cZ3

The bench noted the submissions of petitioner's counsel that the woman was undergoing treatment for symptoms of postpartum psychosis since last year. It asked the medical board to apprise the top court whether there was any evidence to indicate that continuance of pregnancy of the petitioner would be jeopardised by the drugs prescribed for the alleged conditions from which she is stated to be suffering.

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COVID-19: India records 37 fresh infections, active caseload at 349 https://ift.tt/pwR9cZ3

The country's COVID case tally is 4.49 crore (4,49,99,510). The number of people who have recuperated from the disease has increased to 4,44,67,124 and the national recovery rate stands at 98.81 per cent, according to the health ministry's website.

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DaVita sees limited impact from Ozempic's kidney trial success https://ift.tt/pwR9cZ3

The dialysis market has for decades been sustained by high rates of obesity and diabetes, which contribute to kidney damage, but GLP-1 drugs have shown to dramatically improve both conditions.

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Patients suffer after AIIMS-Delhi computer system crashes https://ift.tt/3kspRI1

The computer server at AIIMS, a hospital in New Delhi, crashed causing long delays for patients seeking registration and other services. This is the second time in a year that the hospital's computer systems have failed. Although the hospital claims that the crash was due to maintenance work, sources suggest that it was caused by a software update. The crash affected all patient services, including registration, sample collection, report generation, billing, and admissions. Patients had to wait for hours as manual registration was conducted, causing significant inconvenience.

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Med commission stands by decision to restrict MBBS seats, colleges citing regional disparities https://ift.tt/3kspRI1

The National Medical Commission, the top regulatory body for medical education, has said that its decision will "reduce regional disparities in the availability of healthcare professionals and go a long way in ensuring effective quality of education," a week after chief minister M K Stalin urged the Centre to reverse regulations restricting the opening of new medical colleges.

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IPC officially joins as member of PDG https://ift.tt/3kspRI1

The inclusion of IP in PDG will significantly increase the visibility of the Indian Pharmacopoeia on the international platform. It will establish IP as progressive pharmacopoeia which designs drug quality standards at par with global standards. Application of these standards will lead to the production of world-class pharmaceutical products for domestic and export markets.

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Uzbekistan cough syrup deaths: India allows factory to reopen https://ift.tt/3kspRI1

Marion Biotech, whose cough syrups in Uzbekistan were linked to the deaths of 65 children last year, has been permitted to resume most of its production by the drug controller of Uttar Pradesh. The state drug controller informed that there is no known case of a lack of quality in other medicines manufactured by the firm.

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Israel-Hamas conflict will not significantly impact Indian pharma exports in the region https://ift.tt/3kspRI1

The ongoing Israel-Hamas war will not have much impact or serious effects on Indian pharmaceutical exports, inform pharma experts. As per Pharmexcil, the pharma exports stood at $32.5 million to Israel so far April to August this year. Annual exports are in the order of $ 92 million.

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Is attracting International Medical Graduate the solution to the Doctor Shortage problem of USA ? https://ift.tt/97iZoYv

By 2034, USA might have a shortage of up to 124,000 physicians, states a report by Association of American Medical Colleges. India can be the front runner in solving USA’s Doctor shortage problem as there is absolutely no dearth of talented doctors migrating to USA. Based on American American Physicians of Indian-Origin (AAPI) data, despite comprising less than 1 percent of the U.S. population, Indian Americans make up 9 percent of all doctors and physicians in the country.

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Better eye health could boost Indian economy by US$27bn (₹2.2trn) this World Sight Day https://ift.tt/97iZoYv

Better eye health could boost Indian economy by US$27bn (₹2.2trn) this World Sight Day. New research released this World Sight Day shows avoidable sight loss costs India US$27 billion (₹2.2trn) per year in lost productivity. Indian economy loses more to avoidable sight loss than any other country bar China and the US. 30% of people with sight loss experience a reduction in employment, 90% of vision loss is avoidable with early detection and treatment.

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Drugmaker GSK settles California lawsuit on Zantac https://ift.tt/97iZoYv

GSK on Wednesday said the settlement reflected its "desire to avoid distraction related to protracted litigation." It did not admit any liability and said it would vigorously defend itself in any other Zantac cases.

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India needs 3 psychiatrists per lakh population, has only 0.7 https://ift.tt/e1SVswD

India has a severe shortage of mental health professionals, with only 0.7 professionals for every 100,000 people, far below the recommended ratio of three psychiatrists per 100,000 population. To address this issue, Niti Aayog member Dr V K Paul suggests increasing the number of postgraduate medical seats in psychiatry. Additionally, there is a need to train healthcare workers in Ayushman Bharat - Health and Wellness Centres.

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World Mental Health Day: Time to look beyond the myth & stigma https://ift.tt/e1SVswD

Depressive disorders, anxiety disorders, substance use disorders, schizophrenia, psychotic disorders, bipolar disorder, Post-traumatic stress disorder (PTSD), OCD, and attention deficit hyperactivity disorder (ADHD) are the most common mental health issues in India. ETHealthworld interacted with some industry experts on the current scenario in the mental health industry, including a shortage of mental health professionals and a lack of access to mental healthcare.

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No more hush-hush! End mental health stigma https://ift.tt/e1SVswD

This year, the World Mental Health Day theme is ‘mental health as a universal human right’, which aims to prevent, treat, and enable people with mental health conditions while providing a conducive environment through sensitising people in society. Speaking to ETHealthworld, a few experts shared insights on how the stigma and myths around mental health can be dispelled by creating awareness at the right places with the right age groups.

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Mental health is universal human right, need to destigmatise mental health issues: WHO https://ift.tt/e1SVswD

In countries of the WHO South-East Asia Region, which includes India, one in seven people are living with mental health conditions, she said in a statement. Anxiety and depressive disorders were the commonest conditions among both men and women, contributing to almost 50 per cent of the total number of people living with mental disorders in the WHO South-East Asia Region.

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Study reveals how cancer drug helps to restore immune system's ability to fight tumors https://ift.tt/e1SVswD

A DNA segment known as 9p21, which is frequently deleted in tumours and occurs in 25 per cent-50 per cent of various cancers such melanoma, bladder cancer, mesothelioma, and several brain cancers, is frequently deleted. Long-standing research has shown that malignancies with the 9p21 deletion have worse prognoses for patients and are more resistant to immunotherapies, which are cancer treatments that boost a patient's innate immune system.

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India had world's highest number of preterm births in 2020: Lancet study https://ift.tt/e1SVswD

The research by authors from the World Health Organisation (WHO), the United Nations Children's Fund (UNICEF) and the London School of Hygiene and Tropical Medicine, UK, showed that over 50 per cent of all preterm births in 2020 occurred in just eight countries.

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Nearly 10 million could die of stroke annually by 2050: Lancet report https://ift.tt/uD7gsBv

​The number of stroke deaths in LMICs is projected to rise sharply - widening the gap with HICs - by increasing from 5.7 million in 2020 to 8.8 million in 2050. In contrast, stroke deaths in HICs are estimated to remain largely unchanged at around 900,000 between 2020 and 2050. In 2050, 91% of stroke deaths are projected to be in LMICs compared to 9% in HICs, up from 86% in LMICs and down from 14% HICs in 2020.

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GSK signs shingles vaccine deal with China's Zhifei for around $3 bln https://ift.tt/uD7gsBv

The deal is one of a series of moves by western pharmaceutical firms to seize a bigger share of China's market, including announcements from companies such as AstraZeneca. The vaccine, named Shingrix, is GSK's top-selling medicine. The deal with Zhifei is part of its efforts to reach more than 4 billion pounds ($4.88 billion) in sales by 2026.

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US drugmaker Bristol Myers Squibb buys Mirati for $4.8bn https://ift.tt/uD7gsBv

Bristol Myers Squibb will pay $58 per share in cash "for a total equity value of $4.8 billion," the companies said in a joint statement. In addition, a guaranteed value certificate (GVC) could provide Mirati shareholders with a potential additional $12.00 per share, or up to an additional $1 billion in total.

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Researchers find how genetics helps explain childhood cancer https://ift.tt/uD7gsBv

Researchers at St. Jude Children's Research Hospital found a genetic explanation for why a small percentage of survivors are more likely to develop second cancers, which may be more severe or fatal, using data from the Childhood Cancer Survivor Study (CCSS) and the St. Jude Lifetime Cohort Study (St Jude Life).

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Heartwarming: US doctor donates bone marrow to save a child's life https://ift.tt/Txr4g8l

Dr. Ali Alsamarah, a pediatric doctor in Florida, received a life-changing call informing him that he was a match for a child in need of a bone marrow transplant. Inspired by a friend's similar act, Alsamarah decided to undergo the necessary procedures. The story was shared on the "Good News Movement" Instagram account and received widespread praise and admiration from netizens

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Sun Pharma, Aurobindo recall drugs from US market https://ift.tt/Txr4g8l

As per the USFDA, a Class III recall is initiated in a "situation in which use of, or exposure to, a violative product is not likely to cause adverse health consequences". The US health regulator stated that Aurobindo Pharma is recalling 9,890 bottles of Rasagiline Tablets, a medication indicated for the treatment of Parkinson's disease, from the US.

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Diabetes drugs' use for weight loss risky: Doctors https://ift.tt/Txr4g8l

A study published recently in the Journal of American Medical Association (JAMA), also points to this. This study found that use of GLP-1 agonists for weight loss compared with use of other weight-loss drugs was associated with increased risk of pancreatitis, gastroparesis, and bowel obstruction, but not biliary disease.

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USFDA issues complete response letter for proposed biosimilar Insulin Aspart: Biocon https://ift.tt/Txr4g8l

The company had submitted a comprehensive Corrective and Preventive Action (CAPA) plan in September 2022 that the agency found to be adequate and indicated that it would require a re-inspection of the Malaysia facility prior to the approval of the application.

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SC seeks reply of Centre, states on plea for national programme to tackle muscular dystrophy https://ift.tt/bshHECp

A bench comprising Chief Justice D Y Chandrachud and Justices J B Pardiwala took note of the submissions of lawyer Utsav Singh Bains and issued notices to the Centre and others on the plea.

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Singapore experiencing another COVID-19 wave: Health minister warns https://ift.tt/bshHECp

The spate of these recent cases is driven by mostly two variants - the EG.5 and its sub-lineage HK.3 - both of which are descendants of the XBB Omicron variant.

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National Medical Commission: Doctors shouldn't use unusually large signboards https://ift.tt/bshHECp

The National Medical Commission (NMC) in India has issued guidelines stating that physicians should not use large signboards or include unnecessary information on them. The NMC also emphasizes that the use of titles such as "consultant" or "specialist" should be limited to those who are qualified in the specific specialty. An e-book released by the NMC highlights the consequences of professional errors and warns against misleading the public. The book also addresses issues such as medical negligence and the importance of effective communication between doctors and patients.

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Indian medical students studying in Philippines seek clarity on NMC guidelines https://ift.tt/bshHECp

In a significant turn of events, hundreds of parents of Indian students pursuing medical degrees in the Philippines staged a protest in New Delhi, on Thursday, demanding exemptions from recent regulations issued by the National Medical Commission (NMC). These regulations, issued in a Gazette notification on March 25, 2022, have left the students concerned about the validity of their degrees and the duration of their courses.

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Indian medical students studying in Philippines seek clarity on NMC guidelines https://ift.tt/bshHECp

In a significant turn of events, hundreds of parents of Indian students pursuing medical degrees in the Philippines staged a protest in New Delhi, on Thursday, demanding exemptions from recent regulations issued by the National Medical Commission (NMC). These regulations, issued in a Gazette notification on March 25, 2022, have left the students concerned about the validity of their degrees and the duration of their courses.

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More than 75,000 US health care workers begin 3-day strike https://ift.tt/y4W2Ox5

The walkout of more than 75,000 workers at Kaiser Permanente, the country's largest non-profit health care organisation, comes as surging inflation has spurred industrial action across the US, from Hollywood actors to Detroit auto workers.

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Pondy govt would approve projects for starting new medical colleges by private players: CM https://ift.tt/y4W2Ox5

N Rangasamy, the chief minister of Puducherry, announced on Thursday that the government will approve initiatives from private parties to open medical colleges in the union territory. He claimed that Puducherry students who wanted to study medicine shouldn't have any trouble finding places because the government had already provided a number of resources to make this possible.

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JB Pharma continues winning streak with focus on chronic therapies https://ift.tt/y4W2Ox5

In terms of product and business, almost 48 per cent contribution was coming from chronic therapy, and the endeavour is to reach 60 per cent. As a company, we were traditionally very weak at launching new products, and our new product contribution was less than one per cent. However, we endured the challenge and started developing the life cycle of new brands, said Dilip Singh Rathore

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MediBuddy’s workplace data underscores vital role of early diagnosis in diabetes management https://ift.tt/y4W2Ox5

India accounts for one in seven of all adults living with diabetes globally. Accessibility to high-quality healthcare through telemedicine can help facilitate the uptake of preventive care and further lower health risks, especially in developing countries with a skewed doctor-to-patient ratio.

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Medical device makers may get more time to secure licences https://ift.tt/y4W2Ox5

With the Central Drugs Standard Organisation (CDSCO) missing the October 1 deadline to provide licences to them, it is likely that those manufacturers that have already applied may get an extension for a limited period.

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Is Precision Medicine the future of cardiovascular care? https://ift.tt/RHkMutD

Cardiovascular diseases accounted for most Non-communicable disease (NCDs) deaths, or 17.9 million people annually, followed by cancers (9.3 million), chronic respiratory diseases (4.1 million), and diabetes (2.0 million including kidney disease deaths caused by diabetes), states WHO.

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India finds more toxic syrups months after poisoning deaths https://ift.tt/RHkMutD

This is the first time in at least two years that the Central Drugs Standard Control Organisation (CDSCO) has flagged any DEG and EG contamination in its monthly reports as the country tries to crack down on its $42 billion drug industry dominated by small players.

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Indian-origin CEO of speciality pharma firm agrees to pay USD 20 million to settle kickback allegations https://ift.tt/RHkMutD

BioTek allegedly provided improper physician inducements and covered up kickbacks for patient referrals by waiving co-pays, said US Attorney Jacqueline C. Romero for the Eastern District of Pennsylvania.

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Alembic Pharmaceuticals receives FDA approvals on six of its ANDA during Q2FY24 https://ift.tt/RHkMutD

The company has received six final approvals that include Chlorpromazine Hydrochloride Tablets USP, 10 mg, 25 mg, 50 mg, 100 mg, and 200 mg, Brimonidine Tartrate Ophthalmic Solution, 0.1 per cent, Guanfacine Extended-Release Tablets USP, 1 mg, 2 mg, 3 mg, and 4 mg, Erythromycin Tablets USP, 250 mg and 500 mg, Brimonidine Tartrate and Timolol Maleate Ophthalmic Solution, 0.2 per cent /0.5 per cent, Chlordiazepoxide Hydrochloride and Clidinium Bromide Capsules USP, 5 mg/2.5 mg.

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Malaria vaccine co-developed by Serum Institute will bridge supply gap: Adar Poonawalla https://ift.tt/RHkMutD

As malaria vaccine developed by the University of Oxford and the Serum Institute of India (SII) has been recommended for use by the World Health Organisation (WHO), SII chief Adar Poonawalla said that the combined efforts of both of them have come to fruition.

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Committee formed to investigate Nanded hospital deaths: Maharashtra minister https://ift.tt/8xpgiPs

At least 31 people died in the government-run Dr Shankarrao Chavan Medical College and Hospital reportedly due to an alleged scarcity of medicines. Between Saturday and Sunday, 24 patients were reported to have died with seven more deaths reported today.

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Drugmakers sign on to negotiate Medicare prices under protest https://ift.tt/8xpgiPs

The penalties for not doing so would have been steep: drugmakers would have to pay 65 per cent to 95 per cent taxes on their drug's Medicare sales or withdraw all of their products from the Medicare and Medicaid programs, which together provide health benefits to 158 million Americans.

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Novartis says positive interim results on rare kidney disease drug https://ift.tt/8xpgiPs

IgAN is a rare autoimmune disease mostly affecting young adults, which can lead to kidney failure. The study is to continue for a further 15 months. In total, it will cover around 450 adult patients with primary IgAN who are at high risk of progressing to kidney failure.

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Kariko and Weissman win medicine Nobel for COVID-19 vaccine work https://ift.tt/8xpgiPs

The 2023 Nobel Prize in Physiology or Medicine was awarded to researchers Katalin Kariko and Drew Weissman for their work that made it possible to create COVID-19 vaccinations, the organisation that bestows the prize said on Monday.

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Assessment shows majority of medical colleges have ghost faculty, fall short of 50 per cent attendance requirement: NMC https://ift.tt/L2ckiMY

In a recently notified regulation, the NMC excluded the requirement of an emergency department for setting up new medical colleges. Earlier, in its June 23 draft, emergency medicine department was among the 14 departments that new medical colleges approved for undergraduate admissions must have.

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Assessment shows majority of medical colleges have ghost faculty, fall short of 50 per cent attendance requirement: NMC https://ift.tt/L2ckiMY

In a recently notified regulation, the NMC excluded the requirement of an emergency department for setting up new medical colleges. Earlier, in its June 23 draft, emergency medicine department was among the 14 departments that new medical colleges approved for undergraduate admissions must have.

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Medical colleges could be fined Rs 1 cr for violation of new NMC rules https://ift.tt/L2ckiMY

If a medical college fails to comply with the statutory provisions and regulations as prescribed by the respective boards of the NMC, the commission may also withhold and withdraw accreditation for a period up to five academic years, the regulations said.

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AstraZeneca India gets CDSCO approval for 'Palivizumab' preventive therapy against respiratory syncytial virus https://ift.tt/L2ckiMY

RSV poses a significant global public health challenge, particularly affecting children, and stands as the second most common cause of death in infants under one year of age, following only malaria. The World Health Organisation (WHO) estimates that RSV accounts for over 60 per cent of acute respiratory infections in children and more than 80 per cent in infants under one year old.

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